Welcome to the Essigmann Lab
The Essigmann Lab is in the Department of Chemistry and the Department of Biological Engineering at the Massachusetts Institute of Technology. The research objective of the lab is to understand the relationship between the structures of lesions formed in the genome by DNA damaging agents and the specific biological endpoints of mutation, cancer, and cell death. The goal of our work on carcinogenesis is to probe the molecular etiology of human cancer. Our parallel studies on antitumor drugs focus upon uncovering the mechanism of action of existing drugs. Based upon that understanding, we design novel compounds that could be useful for the treatment of cancer. For more information on the research in the Essigmann lab follow the Lab Research Link.
